Sandalphon (Hebrew: סָנְדַלְפוֹן Sānḏalfōn; Greek: Σανδαλφών: Sandalphon) is an archangel in Jewish and Christian writings, though not in scripture. Sandalphon figures prominently in the mystical literary traditions of Rabbinic Judaism and early Christianity, especially in the Midrash, Talmud, and Kabbalah, and is generally regarded as gathering prayers and transmitting them to God.

Although not explicitly referenced in scripture, some of the earliest sources on Sandalphon refer to him as the prophet Elijah transfigured and elevated to angelic status. Other sources (mainly from the midrashic period) describe him as the "twin brother" of Metatron, whose human origin as Enoch was similar to the human origin of Sandalphon.

Sandalphon's name, which might be related to the Hebrew sandek, godfather (thus corresponding to the tradition of a position occupied by Elijah with regard to the evocation of the prophet in his capacity as protector of unborn children), may also be derived from the Greek prefix sym-/syn-, meaning "together", and adelphos, meaning "brother"; so it might mean "co-brother", as the modern Greek word for "fellow worker" is synadelfos (συνάδελφος), has its roots as seen in the Book of Revelation, chapter, verse. This probably refers to Sandalphon's relationship to Metatron, although this derivation shows uncertain Semitic influences.